Fluid balance should be closely monitored and dehydration must be corrected prior to commencing treatment. Blood serum levels should be measured frequently, especially in patients with renal impairment and the elderly. These should not be taken from the line being used for drug administration.
What blood tests should be monitored when administering gentamicin?
TDM is required for patients on aminoglycosides (e.g. gentamicin, amikacin, tobramycin) and glycopeptides (e.g.vancomycin). Serum concentration monitoring aims to avoid both excessive and sub-therapeutic concentration thereby preventing toxicity and ensuring efficacy.
Why are gentamicin levels monitored?
Serum levels are monitored to reduce the risk of significant accumulation and nephrotoxicity. Dose is adjusted according to age and renal function. Judgement is necessary to decide category of renal function.
What are the contraindications of gentamicin?
Who should not take GENTAMICIN SULFATE?low amount of calcium in the blood.dehydration.a type of movement disorder called parkinsonism.myasthenia gravis, a skeletal muscle disorder.ringing in the ears.disorder of nerve that controls hearing and balance.decreased kidney function.sensation of spinning or whirling.
Who should not use gentamicin?
Before taking this medicine You should not use gentamicin if you are allergic to gentamicin or similar antibiotics such as amikacin, kanamycin, neomycin, paromomycin, streptomycin, or tobramycin.